Lipid composition of human serum lipoproteins

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Lipid composition of human serum lipoproteins.

1. The lipid compositions of the low-density lipoproteins, the high-density lipoproteins and the ultracentrifugal residue of human serum are presented, with emphasis on certain lipoprotein classes and lipid components not previously described. 2. Except for the lipoproteins with the lowest and highest densities, there is a trend for stepwise successive increase or, respectively, decrease in the...

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Lipid composition of lipoproteins of normal human plasma.

It is now established that human blood plasma contains at least three distinct groups of lipoproteins. Although there are several physical methods of isolating lipoproteins, ultracentrifugation has proved to be the most precise. By this means, lipoprotein groups of known mean hydrated density have been isolated and characterized. These differ from each other in peptide composition (1, 2), lipid...

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Apoprotein composition of very low density lipoproteins of human serum.

Methods for quantitation of the major apoproteins of human serum very low density lipoprotein have been developed employing tetramethylurea, which delipidates the lipoprotein and selectively precipitates apolipoprotein B. Six soluble apoproteins are separated by electrophoresis in polyacrylamide gel. One of these is a previously unrecognized species of R-alanine (R4-alanine), more anionic than ...

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Ultracentrifugal studies of lipoproteins of human serum.

In spite of several extensive ultracentrifugal studies of human sera by Mutaenbecher, McFarlane, and Pedersen, the interpretation of the patterns observed has remained in doubt. Specifically, the greatest difficulties encountered by previous workers have arisen in their efforts to study undiluted human sera. McFarlane (1) referred to marked distortions in the pattern observed with undiluted hum...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1967

ISSN: 0006-2936

DOI: 10.1042/bj1040340